Nascent RNA sequencing


Bru-seq refers to a family of related technologies for exploring the dynamics of transcription biology in mammalian cells. The methods are related by the selection and sequencing of only RNA molecules that were metabolically labelled during an exposure of the cells to bromouridine (Bru).

Dr. Wilson has worked for more than a decade with Bru-seq inventor and project leader, Dr. Mats Ljungman, to help develop the associated bioinformatics tools for data analysis. The pipeline and browser that developed by our team have served the needs of researchers worldwide, most recently in work done within the ENCODE Project (publications pending).

Learn more about Bru-Seq